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When asked for the one exercise to do for life to protect the brain, Louisa Nicola chooses the deadlift due to its comprehensive muscle recruitment and neural drive.
Louisa Nicola defines high performance not as constant output, but as the ability to switch between intense focus and recovery.
Louisa explains the compounding danger of sleep deprivation and how a single night of poor sleep can immediately increase the hallmarks of Alzheimer's pathology in the brain.
Nicola discusses how the complexity of human development and neurosurgical miracles make it difficult for scientists to ignore the possibility of a higher power.
Louisa Nicola explains how creatine isn't just for muscles; it's a powerful tool for cognitive function, protecting the brain against stress, concussions, and even sleep deprivation.
Louisa explains the 'biological expiration date' for heart plasticity, emphasizing why midlife is the critical window for intervention.
An explanation of how high blood pressure destroys the tiny capillaries in the brain, leading to a breakdown of the blood-brain barrier.
Louisa explains the 30% drop in brain glucose metabolism during menopause and why a ketogenic diet may be a necessary alternative fuel source.
A description of the glymphatic system and how deep sleep is required to wash out toxic proteins like amyloid beta from the brain.
A breakdown of why the standard 5g dose of creatine isn't enough for cognitive benefits and how high-dose creatine is being used for Alzheimer's patients.
Louisa Nicola breaks down why a racing mind prevents falling asleep and why heat prevents staying asleep, offering specific supplements like GABA and Glycine for each.
A powerful historical example of how extreme physical and emotional hardship can rewire the brain, specifically the AMCC, leading to extraordinary life achievements.
Exploring the critical link between Vitamin D deficiency and dementia, featuring a study on centenarians that highlights a massive risk reduction.
Nicola discusses the negative impact of mindless scrolling and reliance on AI tools like ChatGPT on our cognitive abilities and attention spans.
A deeply personal story about Louisa's grandmother that fuels her passion for female-focused neurohealth and the systemic issues in medical literature.
Louisa Nicola discusses a landmark study showing that four hours of specific exercise per week can remodel a 50-year-old heart to look like a 30-year-old heart.
A specific, actionable exercise protocol designed to maximize VO2 max, which is cited as the strongest predictor of all-cause mortality.
Louisa Nicola reveals a shocking truth about fish oil supplements: 95% of popular brands are rancid, and keeping them at room temperature makes them worse.
Louisa recommends daily blood pressure monitoring as a cheap and effective way to prevent the breakdown of brain capillaries.
A simple, actionable tip to combat the negative effects of being 'active sedentary' by performing brief intervals of air squats every hour.
A powerful revelation that Alzheimer's is largely a disease of lifestyle rather than genetics, offering hope that most cases can be avoided through early intervention.
Louisa Nicola explains the Anterior Midcingulate Cortex (AMCC), often called the 'willpower muscle,' and how it physically grows when we engage in activities we find difficult or resistant.
Louisa Nicola explains a powerful biohack using high-dose creatine to reverse the cognitive decline associated with a bad night's sleep.
A stark warning about the immediate impact of sleep deprivation on the buildup of Alzheimer's-related proteins.