Click any moment to jump to that point in the video
Dr. Alan Goldhammer introduces his lifelong dedication to the principle that "health results from healthful living," explaining his early interest in this field. This clip provides personal context for his expertise.
This clip begins to explain the "complex physiological adaptation" the human body undergoes during fasting, starting with the brain's normal reliance on glucose and setting the stage for the metabolic shift.
This clip addresses the nuance of fasting as a "survival mechanism" versus a "healthy practice." Dr. Goldhammer explains that while it's a natural adaptation, its application today is unique, addressing the consequences of consistent dietary excess in modern society.
This clip explains the initial metabolic shift during fasting, where the body transitions from primarily using glucose to producing ketones as a fuel source, a process that progresses over the first 24-48 hours depending on glycogen stores.
The host summarizes the metabolic shift during fasting: moving from a glucose-burning state (typical Western diet) to an evolutionary switch where the body burns fat and produces ketones for brain fuel. This simplifies a complex concept.
Learn the precise protocol for reintroducing food after a water fast, starting with juices and gradually adding fiber, to avoid digestive challenges and ensure a smooth transition back to a healthy diet.
This clip confirms the 24-hour window during which the body uses glycogen stores for glucose. It then explains the metabolic dilemma after depletion, where the body must choose between burning fat or breaking down lean tissue.
Learn the strict safety protocols for medically supervised water-only fasting. This clip explains that no electrolytes or vitamins are given, but blood levels (like potassium and sodium) are rigorously monitored. If reserves drop too low, the fast is terminated and refeeding with broths begins, ensuring patient safety.
This clip highlights the paradox of our modern world, where obesity is rampant and people seek quick fixes, yet remain unaware of fasting's ancient, proven health benefits. It sets the stage for a deeper dive into why fasting is essential.
Explore the unique benefits of fasting for women's health, specifically addressing conditions like fibrocystic breast disease, dysmenorrhea, menorrhagia, and PCOS, which are often linked to excess estradiol. The clip explains how fasting profoundly affects gut microbiome and liver function, crucial for estradiol breakdown, leading to significant improvements.
Explore the differences between water fasting and ketogenic diets for visceral fat loss, with an argument for water fasting's superior efficiency. This clip also critiques high-protein keto diets, linking excess animal protein to cardiovascular disease, cancer, and inflammation, advocating for a whole plant food, SOS-free approach.
Discover the meaning behind 'SOS' in the context of diet: Sugar, Oil, and Salt, which are identified as the chemicals added to food that contribute to illness and weight gain, and why an SOS-free diet is crucial post-fasting.
This clip sets up a key comparison between intermittent fasting and simple calorie restriction, posing the question of whether they are the same and which approach is more effective, especially in a world of hyper-palatable foods.
This clip provides historical context, explaining that for ancient ancestors, getting enough food was a primary struggle, making dietary excess a relatively new phenomenon. It highlights how modern abundance contrasts sharply with our evolutionary past.
This clip ties the historical context of scarcity to the modern problem of "dietary excess" (too many calories), explaining how a natural biological adaptation like fasting is now applied to counteract the diseases of modern abundance.
Learn the essential steps to ensure a safe fasting experience, including medical history review, kidney and liver function checks, and the critical importance of resting to prevent lean tissue loss.
This clip provides crucial nuance regarding intermittent fasting, stating that an 8-hour feeding window may not be suitable for everyone, especially competitive athletes with high caloric needs. It advises considering individual energy requirements.
This clip offers practical guidelines for adjusting feeding windows based on caloric needs, suggesting a 12-hour window for those burning high calories (e.g., athletes) and reiterating the benefit of a narrower window for most people focused on weight maintenance or loss.
This clip explains the rationale behind using highly purified water (like distilled or reverse osmosis) during fasting: to remove "hydrogenated hydrocarbons and the chlorine and everything out of the water," ensuring the purest possible intake, akin to "rain water if the environment wasn't" polluted.
This clip outlines the practical advantages of juice fasting: it can be done without modifying medications and safely at home, unlike water fasting which often requires a controlled setting. This makes it more accessible for some.
Dr. Goldhammer recounts his pivotal experience studying with Alec Burton, a leading expert in medically supervised water-only fasting in Australia, where he observed "things that weren't supposed to be happening" – people getting better from chronic diseases. This is a powerful origin story for his work.
This clip explains the specific, limited scenario where juice fasting *can* be helpful: for people addicted to the artificial dopamine stimulation of refined diets who are trying to make a dietary break. Its sweetness makes it an appealing transition tool.
This clip compares juice fasting to water fasting, stating that while juice can help avoid processed foods, water fasting offers "advantages... in terms of the magnitude of the detoxifying effect," highlighting its superior impact.
This clip details what happens after approximately 24 hours of fasting: the depletion of glycogen stores, forcing the body to choose between burning fat or breaking down muscle for glucose. It highlights the critical metabolic shift.
This clip summarizes the overarching problem: seemingly disparate chronic diseases are all linked to dietary excess, excess fat, visceral fat, and the resulting inflammation. It sets up the next section on how fasting addresses this.
This clip details the brain's metabolic transition during fasting, explaining how it shifts from burning glucose to predominantly using ketones (specifically beta hydroxybutyric acid), which are byproducts of fat metabolism.
Dr. Goldhammer mentions his extensive published research and book, "Can Fasting Save Your Life?", emphasizing the core principle that fasting helps the body heal itself by getting "out of the way." This positions fasting as a natural, powerful intervention.
This clip clarifies Dr. Goldhammer's specific definition of therapeutic fasting: "the complete abstinence of all substances in an environment of complete rest." This sets a precise context for his recommendations, distinguishing it from other popular fasting methods.
Discover the unexpected psychological benefits of fasting, including enhanced willpower, discipline, and motivation. Learn how a prolonged fast can reprogram your brain, making the idea of skipping a meal far less terrifying and dispelling illogical fears about depletion.
This moment highlights the often-underestimated psychological benefits of fasting, including the sense of accomplishment, dopamine rebalancing, and taste adaptation. The host shares how a ketogenic diet provided a similar 'tremendous reset' for habits and cravings.
Explore how water fasting consistently helps patients with Polycystic Ovarian Syndrome (PCOS), even when diet changes alone have failed. Learn about the potential for normalizing menstrual cycles, aiding fertility, and the role of gut microbiome in hormonal balance.
Learn how water fasting can be used for weight loss, including typical daily weight loss (around one pound) and how to estimate fast duration for specific weight goals. Understand the importance of monitoring to achieve optimal health without depletion.
This clip explains how fasting specifically targets visceral fat, the harmful fat around organs, which is linked to severe inflammatory diseases like heart disease, cancer, and diabetes. It's a key benefit beyond simple weight loss.
Dr. Goldhamer discusses how conventional medical advice can lead to 'learned helplessness' by telling patients their conditions are permanent. He explains how fasting can shatter this paradigm, empowering individuals by demonstrating their ability to overcome seemingly hopeless health problems.
This clip explains the remarkable adaptation of the human brain, which switches from burning glucose to burning fat (ketones) during prolonged fasting. This crucial mechanism prevents starvation and allows for extended periods without food.
This clip reveals the astonishing capacity of the human body to fast for extended periods, stating that a 70kg male could theoretically fast for up to 70 days, thanks to the brain's ability to switch to burning fat.
This clip clarifies that Dr. Goldhammer's extensive research is based on "water only fasting," where people fast from 5 to 40 days. It highlights the intensity of his work and sets up the next question about who undergoes such long fasts.
This clip highlights the wide-ranging and significant health benefits of fasting, positioning it as a powerful solution for major health problems like high blood pressure, insulin resistance, cognitive function, depression, and anxiety. It's a strong hook for the topic.
This clip reveals a surprising parallel between fasting and exercise: both trigger similar beneficial chemical changes, like increasing BDNF, which protects the brain from diseases like Alzheimer's. It also briefly introduces water fasting as a solution for conditions resistant to medication.
This clip presents compelling evidence from Dr. Goldhammer's work, detailing a study where 174 consecutive patients with high blood pressure successfully normalized their blood pressure and got off medication through fasting. It offers concrete results.
This clip explains the crucial role of rest during therapeutic fasting. It highlights that being active forces the body to produce more glucose, which can undermine the fasting process by potentially leading to lean tissue breakdown instead of maximizing fat loss.
This clip elaborates on the importance of rest during fasting to prevent lean tissue breakdown (gluconeogenesis) and instead maximize fat loss. It's a key piece of advice for anyone looking to fast effectively without losing muscle.
This clip connects the human brain's disproportionately large size and high glucose consumption to the necessity of fasting as a survival mechanism. It explains that without the ability to switch fuel sources, early humans wouldn't have survived periods of food scarcity.
This clip reveals a fascinating historical fact: modern prevalent diseases like heart disease, diabetes, and certain cancers were once rare "diseases of kings," afflicting only the wealthy who could consistently overeat. It highlights the dramatic shift in global health patterns.
This clip explains how diseases once rare for common people are now widespread due to consistent dietary excess. Crucially, it highlights how chemicals in modern food "fool our brain satiety mechanisms" into overeating, a critical insight into the obesity crisis.
This clip exposes how visceral fat releases inflammatory products leading to a range of seemingly unrelated conditions: heart disease, cancer, diabetes, and autoimmune diseases. It critiques the medical system for treating these as independent issues, missing the common root cause.
This clip explains the direct link between beta hydroxybutyric acid (a ketone) and the production of BDNF (Brain-Derived Neurotrophic Factor), a neurochemical crucial for protecting the brain from oxidative damage and conditions like Alzheimer's disease.
This clip describes a compelling rat study showing that exercise prevents Alzheimer's disease by increasing BDNF. It sets up the parallel with fasting's effects on brain health.
This clip completes the explanation of the common mechanism between fasting and exercise: both reduce visceral fat and the inflammation that drives chronic diseases. It reinforces their similar benefits.
This clip introduces a compelling rodent study demonstrating that periodic fasting can significantly increase lifespan, even with the same diet, linking fasting to extended longevity.
This clip elaborates on the rodent study, showing that periodic fasting or systematic underfeeding (60% of ad libitum intake) can dramatically increase lifespan by 30% to 100%, even when the overall diet is the same.
This clip clarifies that fasting allows organisms to live their full lifespan by reversing the negative consequences of dietary excess, particularly inflammation. It also directly addresses the question of whether calorie restriction is the same as fasting.
This clip provides a clear example of how food chemicals override natural satiety. Eating whole plant foods leads to natural fullness, but adding certain chemicals to food makes people eat "significantly more" before feeling satiated, exposing a key mechanism of overeating.
This clip introduces time-restricted feeding, a form of intermittent fasting practiced for 40 years, advising listeners to avoid eating 3-4 hours before bed. This offers a simple, actionable step for daily fasting.
This clip provides practical advice on extending a daily 12-hour fast to 16 hours for weight loss, suggesting to add 4 hours in the morning and incorporate exercise to preferentially burn fat.
This clip explains a key benefit of limiting the feeding window to 8 hours: it helps curb overeating driven by boredom, tiredness, or fatigue, rather than genuine hunger. It highlights the psychological aspect of eating.
The host shares a personal observation: significantly improved cognitive performance when on a ketogenic diet or fasted, contrasting it with diminished clarity on a typical Western diet. This sets up the explanation for this common experience.
This clip offers a critical clarification: juice fasting is not "technically fasting" because true fasting involves complete abstinence from all substances. It defines juice fasting as a "modified form of eating" that is high in sugar and very low in fiber.
This clip explains the strict protocol for medically supervised water fasting: patients consume "fractionally steamed distilled water only," with no supplements or medications. It emphasizes the purity and controlled nature of the intervention.
Understand the critical importance of medical monitoring during fasting for dehydration and electrolyte changes, and the severe, potentially fatal risks of refeeding syndrome if refeeding is too rapid or unsupervised.
Hear about a prospective study demonstrating the powerful long-term effects of fasting on hypertension, with 76% of participants maintaining normal blood pressure and weight loss a year later, highlighting the sustainability of behavioral changes.
Delve into the precise body composition changes during fasting, backed by DEXA scanner data, revealing how a two-week fast leads to significant visceral fat loss (40%) with minimal, recoverable lean tissue loss (6%), and continued fat loss post-fasting.
Discover why fasting is a more efficient method for mobilizing visceral fat compared to diet alone. This clip also offers a controversial perspective: medications for high blood pressure treat the diet, not the condition, and changing your diet can immediately reduce the need for drugs.
Learn how fasting acts like a 'reboot' for the body, particularly for the gut microbiome. This clip explains how fasting causes a significant drop in gut organisms, allowing for a strategic repopulation during refeeding, similar to flashing a computer's memory.
Discover the profound impact of careful refeeding after fasting on gut microflora balance, and its link to improving GI conditions like ulcerative colitis and Crohn's disease. This clip also highlights the surprising connection between gut health and mental well-being, including depression and anxiety, due to dopamine and serotonin production in the gut.
Challenge your understanding of 'cure' in medicine. This clip explains that conditions like obesity and high blood pressure are managed, not cured, emphasizing that while symptoms can normalize, the underlying causes must be continually addressed through lifestyle changes to prevent relapse, going beyond the typical 5-year survival definition of a medical 'cure'.
Understand the powerful mechanism behind fasting: by reducing the body's digestive workload, energy is redirected to heal accumulated problems like excess fat, diabetes, and autoimmune diseases. This clip details how fasting helps repair gut leakage, which is often implicated in conditions where the immune system attacks its own tissues.
Discover surprising benefits of fasting for healthy individuals, including lower cholesterol and blood pressure, and a reduction in body fat. Learn recommended fasting frequencies for optimal preventative health, and why many people who think they're healthy might not be.
Understand why visceral fat (belly fat) is so dangerous, acting like a 'tumor' and causing inflammation. Learn the evolutionary reasons our bodies store fat, and how fasting uniquely and preferentially mobilizes this harmful visceral fat, preserving essential tissues.
Understand the main safety concerns associated with water fasting, such as orthostatic hypotension (dizziness) and dehydration, and how these risks are managed through careful monitoring. Learn why medical supervision and proper protocols are essential for safe and effective fasting.
Dr. Goldhamer outlines three essential characteristics—honesty, integrity, and intelligence—that everyone should aspire to for success and happiness, explaining how they contribute to effective decision-making and relationships.
Hear the incredible 10-year story of a young woman who achieved remission from follicular lymphoma through a 3-week water fast and a whole plant food, SOS-free diet, despite her oncologist's advice that diet didn't matter. This case, published in BMJ, highlights the potential of lifestyle interventions in cancer management.
This clip explains that ketogenic diets and fasting create stable glucose and insulin levels, eliminating the "sugar roller coaster" that impairs cognitive function. It advises seeking stability for important mental work.
This clip provides a profound insight into why fasting and exercise share similar benefits, despite their apparent differences. Dr. Goldhammer suggests both "undo the consequences of dietary excess," offering a unifying theory for their positive health impacts.
This clip explains why a typical diet harms cognitive function: refined carbohydrates cause insulin spikes, leading to blood sugar crashes ("vacasillations") that directly interfere with mental clarity and performance.
This clip offers straightforward advice for combating non-hunger-driven eating: "When you're tired, go to sleep. And uh when you're bored, you know, engage in productive activities. And when you're hungry, then you eat." It promotes mindful eating and self-awareness.
This clip explicitly connects the brain-protective effects of exercise (via BDNF) to fasting, stating that BDNF levels are dramatically higher with both. It sets up the idea that fasting offers similar "cardabolic improvements" to physical activity.
This clip explains how our evolutionary drive to value "richer foods" for survival in times of scarcity is now exploited. In a world with "unlimited amounts of hyperconcentrated foods" (with salt, oil, sugar), our natural instincts lead to overeating and a "corrupted system."
This clip explains the fundamental challenge of simply "not eating as much": modern food manufacturers add chemicals that "fool your satiety mechanisms," making it incredibly difficult to avoid overeating and the resulting excess fat.
Dr. Goldhammer offers a profound reframe of longevity studies: "It's not that fasting doubles your lifespan. It's overfeeding cuts it in half." He argues that overfeeding leads to fat and visceral fat, shortening life, making fasting a way to restore natural lifespan.
Dr. Goldhamer challenges the common misconception that health comes from external treatments rather than fundamental healthful living, highlighting society's 'pleasure trap' and the importance of delayed gratification in achieving true well-being.
This clip explains the evolutionary root of our cravings for high-caloric density foods (with salt, oil, sugar): more dopamine equals more pleasure. Our brains evolved in scarcity, valuing rich foods, but this mechanism is now exploited by modern food, leading to overconsumption.
This clip provides a clear and concise definition of autophagy, describing it as the body's process for getting rid of senescent cells, waste products, and even cancer cells, essentially "eating up debris and doing the housekeeping." It highlights a key benefit of fasting.
This clip vividly describes visceral fat, the dangerous fat around organs, as "pro-inflammatory, hyper metabolic, hypertrophic," and acting "like a tumor." It's a powerful warning about the dangers of obesity and its specific type of fat.
This clip critically identifies salt, oil, and sugar as "not food" but rather "hyperconcentrated components" designed to make food "taste better" by stimulating dopamine in the brain. It exposes the addictive nature of processed foods.